At the bottom of the Premier Division table, Stalybridge Celtic have recently added reinforcements with the signings of James Ellison, Jordan Helliwell and Will Goodwin.
Simon Haworth’s side have recorded one draw and three losses so far this season, and travel to Atherton Collieries who sit 12th in the league table.
Stafford Rangers hold the same record as Celtic just one place above, and travel to Broadhurst Park to face FC United of Manchester, who are also playing for their first league win.
Neil Reynolds’ side are just 90-minutes away from the FA Cup first round proper, and will host Guiseley in the fourth round qualifier.
With two draws and two losses, Grantham Town host Lancaster City, who are also searching for their first league win with just three games played.
Grantham Town recently added former Sheffield Wednesday winger Jack Stobbs to their squad, who could make his debut this weekend.
At the top of the table, Warrington Town will be looking to bounce back from their first defeat of the season last weekend away to Mickleover as they host Radcliffe, who sit 13th in the table.
Radcliffe recently announced the signing of experienced midfielder Neil Danns.
In third spot, Witton Albion travel to Gainsborough Trinity, while South Shields host Matlock Town.
Following their 3-2 victory over the Yellows, their second win of the season, Mickleover travel to Hurst Cross Stadium to play Ashton United.
Basford United host Bamber Bridge, while Nantwich Town travel to Scarborough Athletics.