It has been a difficult last seven days for the Mariners, who were forced to rescue a late equaliser at Stalybridge Celtic last Saturday before falling to a 2-1 defeat at home to FC United of Manchester in midweek.
They will face a Hyde side also looking to return to winning ways following their 1-0 defeat at second-placed Radcliffe last weekend.
In the weekend’s other notable action, second faces off against fourth as Radcliffe welcome Warrington Town to the Neuven Stadium.
It will be a tough test of the Boro’s promotion credentials, up against a Yellows side that are currently on a club-record 16-match unbeaten run in the league.
Further down the division, there are some big games in the fight for survival, with the bottom three all at home.
Two of the sides looking to steer themselves closer to safety, Morpeth Town and Stalybridge Celtic, will also meet at Craik Park.
All fixtures will take place on Saturday 18 March at 3pm, unless stated otherwise.
Fixtures - Saturday 18 March
Ashton United v Atherton Collieries
Bamber Bridge v Whitby Town
Belper Town v Lancaster City
Gainsborough Trinity v Nantwich Town
Hyde United v South Shields
Liversedge v Stafford Rangers
Marine v FC United of Manchester
Marske United v Matlock Town
Morpeth Town v Stalybridge Celtic
Radcliffe v Warrington Town
Warrington Rylands v Guiseley
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